Applied Spine Technologies

New Haven, CT

Private

Applied Spine is developing non-fusion surgical procedures to address lower back pain.

Articulinx, Inc.

Mountain View, CA

Private

Articulinx, Inc is developing minimally invasive implants for the treatment of osteo-arthritis.

Avedro, Inc.

Waltham, MA

Private

Avedro, Inc. is developing a non-incisional refractive surgery procedure for treating myopia.

Axogen

Gainesville, FL

Private

Axogen is developing a proprietary nerve graft to repair and regenerate damaged peripheral nerves.

Bayhill Therapeutics

Palo Alto, CA

Private

Bayhill Therapeutics develops products for the treatment of autoimmune diseases.

Benvenue

Mountain View, CA

Private

Benvenue is developing minimally invasive products to treat diseases of the spine.

CardioMind

Sunnyvale, CA

Private

CardioMind is developing a guidewire-sized stent delivery technology. CardioMind's platform offers a unique approach to low profile, less traumatic delivery of stents with applications in cardiovascular, neurovascular and peripheral artery disease.

Cartilix

Foster City, CA

Private

Cartilix is developing a device and associated biomaterials to treat focal cartilage defects in joints.

CryoVascular Systems

Los Gatos, CA

(Acquired by Boston Scientific)

CryoVascular Systems has developed a cryogenic balloon catheter for treating disease in coronary and peripheral arteries.

EBR Systems

Sunnyvale, CA

Private

EBR Systems is developing novel technology for wireless cardiac stimulation.

Endogastric Solutions

Redmond, WA

Private

EndoGastric Solutions is developing incision-less transoral procedures for the treatment of upper gastrointestinal diseases.

Facet Solutions

Logan, UT

Private

Facet Solutions is developing surgical devices to treat spinal stenosis.

Favrille

San Diego, CA

(NASDAQ: FVRL)

Favrille has developed individualized treatment for patients with relapsed follicular B-cell non-Hodgkin’s lymphoma.

Flowmedica

Fremont, CA

Private

Flowmedica develops minimally invasive intravascular systems for the prevention and treatment of kidney dysfunction.

Fox Hollow Technologies

Redwood City, CA

(NASDAQ: EVVV)

Fox Hollow Technologies has developed a unique device to remove plaque or diseased tissue from coronary and peripheral arteries. Fox Hollow Technologies merged with ev3, Inc. (NASDAQ: EVVV) in October 2007.

Hansen Medical

Mountain View, CA

(NASDAQ: HNSN)

Hansen Medical develops automated solutions to enhance catheter placement for interventional cardiovascular procedures.

HemaQuest Pharmaceuticals

Boston, MA

Private

HemaQuest Pharmaceuticals is developing treatments for serious blood disorders.

Informed Medical Communications

New York, NY

Private

Informed Medical is an interactive medical information services provider that enables biopharmaceutical companies to market directly to physicians and patients.

InSound Medical

Newark, CA

Private

InSound Medical is a company developing leading edge technologies for the hearing impaired.

iScience Interventional

Menlo Park, CA

Private

iScience has developed an ocular imaging system and a catheter-based technology to treat glaucoma.

Kolis Scientific

Morrisville, NC

Private

Kolis Scientific is developing an office based procedure for the treatment of a common ophthalmic condition.

Lumend

Redwood City, CA

(Acquired by Cordis/Johnson & Johnson)

LuMend develops devices to treat chronic total occlusions (CTOs) in the peripheral and coronary arteries.

Luminous Medical

Carlsbad , CA

Private

Luminous Medical is developing a minimally invasive device to monitor blood glucose to ensure tight glycemic control in a critical care setting.

M2 Medical

Sunnyvale, CA

Private

M2 Medical is developing a disposable drug delivery system which initially will be used for insulin delivery for Type I diabetics.

MicroVention

Aliso Viejo, CA

(Acquired by Terumo)

MicroVention sells a unique catheter-based implant for the treatment of cerebral aneurysms as an alternative to an invasive craniotomy.

MyoScience

Redwood City, CA

Private

Myoscience is developing a novel product for the dermatology market.

OncoMed Pharmaceuticals

Redwood City, CA

Private

OncoMed, Inc. is developing antibody therapeutics targeting cancer stem cells, a cancer cell population responsible for cancer growth, recurrence, and metastases.

Ovalis

Mountain View, CA

Private

Ovalis is developing catheter based devices for the repair of various cardiac defects.

Paracor Medical

Sunnyvale, CA

Private

Paracor Medical has developed minimally invasive products to treat congestive heart failure.

PhotoThera

Carlsbad, CA

Private

PhotoThera is developing medical devices to reduce the debilitating effects of stroke.

Point Biomedical

San Carlos, CA

Private

Point Biomedical is developing and testing proprietary contrast agents and drug delivery technologies.

Pulmonx

Palo Alto, CA

Private

Pulmonx is developing a minimally invasive therapy for the treatment of emphysema.

Reduction Technologies

Santa Clara, CA

Private

Reduction Technologies Inc. is developing a minimally-invasive spinal implant for the non-fusion treatment of scoliosis.

Renovis

South San Francisco, CA

(NASDAQ: RNVS)

Renovis develops drugs for the treatment of neurological and psychological diseases.

SenoRx

Aliso Viejo, CA

(NASDAQ: SENO)

SenoRx develops and sells products used in the diagnosis and therapy of breast disease.

Sierra Surgical Technologies

Palo Alto, CA

Private

Sierra Surgical is developing a minimally invasive surgical surgical system.

Simpirica

Redwood City, CA

Private

Simpirica is developing a minimally invasive spinal implant for treating discogenic back pain.

Spectragenics

Pleasanton, CA

Private

Spectragenics develops therapeutic, light-based aesthetic devices for the consumer market.

Spinal Kinetics

Sunnyvale, CA

Private

Spinal Kinetics develops innovative devices for preservation of motion of the spine.

Spinal Modulation

Menlo Park, CA

Private

Spinal Modulation is developing therapeutic devices for the treatment of chronic pain.

Spiracur, Inc.

Fremont, CA

Private

Spiracur is developing novel technology for the wound care market.

Synergeyes

Carlsbad, CA

Private

SynergEyes develops and sells a hybrid contact lens for vision disorders.

Talima Therapeutics

San Carlos, CA

Private

Talima is developing an innovative drug delivery system, with a clinical focus in podiatry and dermatology.

TriVascular

Santa Rosa, CA

(Acquired by Boston Scientific)

TriVascular develops next-generation endovascular grafts for the treatment of aortic aneurysms.

VeinRx

Miami, FL

Private

VeinRx is developing minimally invasive devices for the treatment of varicose veins.

Ventus Medical

Belmont, CA

Private

Ventus Medical is developing a novel means of treating respiratory diseases.

Vitreo Retinal Technologies

Irvine, CA

Private

Vitreo Retinal Technologies, Inc. is developing novel therapeutics for the treatment of serious ocular diseases.

WaveTec Vision

Aliso Viejo, CA

Private

WaveTec Vision is developing ORange™, a novel wavefront meaurement technology that provides on-demand, intraoperative information to the refractive cataract surgeon.